The author declared that diosgenin, restrain STAT3 signaling way leading to inhibition of multiplication and chemosensitization of liver tumor cells Overexpression of active STAT3 release diosgenin tempt apoptosis. The mutations block the use of the G1, G2, and M checkpoints in the cell […]. At a cellular basis, cancer cells are not that different from normal cells. In fact, from a biological view point cancer cells originate from normal cells.
Mitosis and Meiosis
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Mitosis and meiosis are both forms of cell division, however, their processes are not identical. Mitosis happens in somatic cells cells that are not gametes , and it produces two genetically identical daughter cells. Mitosis happens to replace dead or damaged cells or during growth. Mitosis consists of 4 phases: prophase, metaphase, anaphase, and telophase. DNA replication happens during S phase which is before the mitotic phase. During prophase, the chromatin condense into chromosomes, and the mitotic spindle forms textbook,
The Importance Of Mitosis
Cancer stem cells are responsible for tumor initiation, progression, relapse, metastasis, and drug resistance. Common cancers Topoisomerase inhibitor drugs treat are leukemia, lung, and ovarian cancers. A disadvantage to taking Topoisomerase inhibitor drugs is that there is a greater chance of being diagnosed with a second cancer. Mitotic inhibitor drugs are plant alkaloids that come from natural products and work by stopping mitosis or enzymes from making the proteins that the cancer cell would need to produce more.
The two main phases that occur during a cell cycle are interphase and mitosis. During most of a cell cycle, the cell spends a majority of its time in interphase resting in the cell cycle. Within interphase, the cell goes through 3 phases; 2 growth phases and DNA replication.