Metrics details. Northern Darfur State at western Sudan region has a multiethnic population with a high frequency of sickle cell anaemia, but little about it is published. The prevalence of sickle cell disease by haemoglobin electrophoresis among these children patients was 59 Sickle cell trait patients were Individuals with sickle cell trait had haematological parameters near to those of normal individuals. Sickle cell anaemia SCA is an autosomal recessive blood disorder lead to the production of red blood cells that appear abnormal.
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Sickle-Cell Anemia is a genetic blood disorder caused by the presence of an abnormal form of hemoglobin. These hemoglobin molecules tend to aggregate after unloading oxygen forming long, rod-like structures that force the red cells to assume a sickle shape. Unlike normal red cells, which are usually smooth and malleable, the sickle red cells cannot squeeze through small blood vessels. When the sickle cells block small blood vessels, the organs are deprived of blood and oxygen.
The air sacs in the lungs fill with pus and other liquid. Oxygen has trouble reaching you blood. Because of this and spreading infection through the body pneumonia can cause death. Since then, the use of antibiotics brought it under control. In , pneumonia and influenza combined ranked as the sixth leading cause of death.